Kuo-Chen Cheng Selected Research

obtusilactone A

12/2010

Obtusilactone A and (-)-sesamin induce apoptosis in human lung cancer cells by inhibiting mitochondrial Lon protease and activating DNA damage checkpoints.

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Kuo-Chen Cheng Research Topics

Disease

9	Respiratory Insufficiency (Respiratory Failure) 01/2020 - 10/2009
6	Infections 12/2016 - 06/2006
5	Lung Injury 01/2017 - 06/2002
4	Chronic Obstructive Pulmonary Disease (COPD) 01/2022 - 02/2010
4	Neoplasms (Cancer) 10/2020 - 06/2010
4	Inflammation (Inflammations) 12/2014 - 12/2004
3	Respiratory Distress Syndrome (Acute Respiratory Distress Syndrome) 01/2017 - 07/2009
3	Pneumonia (Pneumonitis) 12/2014 - 06/2002
2	Liver Cirrhosis (Hepatic Cirrhosis) 01/2020 - 03/2017
2	Renal Insufficiency (Renal Failure) 05/2019 - 12/2016
2	Critical Illness (Critically Ill) 08/2018 - 01/2007
2	Lung Neoplasms (Lung Cancer) 07/2018 - 12/2010
2	Chronic Kidney Failure (Chronic Renal Failure) 01/2017 - 10/2015
2	Ventilator-Induced Lung Injury 12/2014 - 07/2009
2	Bacteremia 06/2006 - 05/2003
1	Acidosis 01/2021
1	Colorectal Neoplasms (Colorectal Cancer) 01/2020
1	Prostatic Neoplasms (Prostate Cancer) 01/2020
1	Hemorrhage 05/2019
1	Liver Failure 05/2019
1	Clostridium Infections 08/2018
1	Dementia (Dementias) 01/2017
1	Severe Dengue 12/2016
1	Abdominal Pain (Pain, Abdominal) 12/2016
1	Tuberculosis (Tuberculoses) 11/2016
1	Carcinogenesis 09/2015
1	Leukemia 09/2015
1	Hematologic Neoplasms (Hematological Malignancy) 09/2015
1	Lung Abscess 04/2015
1	Cicatrix (Scar) 01/2015
1	Acne Vulgaris 01/2015
1	Melanosis (Freckles) 01/2015
1	Wounds and Injuries (Trauma) 01/2012
1	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 12/2010
1	Edema (Dropsy) 07/2009
1	Hemorrhagic Shock 07/2009
1	Liver Abscess 09/2008
1	Necrosis 01/2008

Drug/Important Bio-Agent (IBA)

6	CytokinesIBA 12/2014 - 06/2002
3	Oxygen (Dioxygen)IBA 05/2019 - 07/2006
2	Indicators and Reagents (Reagents)IBA 01/2020 - 05/2006
2	Urea (Carbamide)FDA LinkGeneric 01/2017 - 07/2006
2	NitrogenIBA 01/2017 - 07/2006
2	C-Reactive ProteinIBA 12/2016 - 12/2005
2	Lactic Acid (Lactate)FDA LinkGeneric 12/2016 - 07/2006
2	Anti-Bacterial Agents (Antibiotics)IBA 11/2016 - 03/2014
2	FluoroquinolonesIBA 11/2016 - 01/2008
2	Capsules (Microcapsules)IBA 04/2015 - 04/2007
2	LipopolysaccharidesIBA 12/2014 - 01/2008
2	Rifampin (Rifampicin)FDA LinkGeneric 11/2013 - 04/2012
2	AntioxidantsIBA 01/2012 - 06/2010
2	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 01/2008 - 07/2006
2	Interleukin-10 (Interleukin 10)IBA 01/2008 - 12/2004
1	Bronchodilator Agents (Bronchodilators)IBA 01/2022
1	Sodium Bicarbonate (Baking Soda)FDA LinkGeneric 01/2021
1	Carbapenems (Carbapenem Antibiotics)IBA 08/2018
1	pro-brain natriuretic peptide (1-76)IBA 01/2017
1	Natriuretic PeptidesIBA 01/2017
1	AlbuminsIBA 12/2016
1	Thromboplastin (Tissue Factor)IBA 12/2016
1	Pregnenolone Carbonitrile (PCN)IBA 11/2016
1	ResistinIBA 09/2015
1	LeptinIBA 09/2015
1	AdiponectinIBA 09/2015
1	AdipokinesIBA 09/2015
1	Melanins (Melanin)IBA 01/2015
1	Glutamine (L-Glutamine)FDA Link 12/2014
1	EndotoxinsIBA 12/2014
1	Third Generation CephalosporinsIBA 03/2014
1	Tetracycline (Achromycin)FDA LinkGeneric 03/2014
1	(10)-shogaolIBA 01/2012
1	Protease La (Endopeptidase La)IBA 12/2010
1	Caspase 3 (Caspase-3)IBA 12/2010
1	sesaminIBA 12/2010
1	obtusilactone AIBA 12/2010
1	Adenosine A2A Receptor (Adenosine A2A Receptors)IBA 07/2009
1	IronIBA 09/2008
1	Virulence Factors (Pathogenicity Factors)IBA 09/2008
1	AllantoinIBA 09/2008
1	aerobactinIBA 09/2008
1	SiderophoresIBA 09/2008
1	Levofloxacin (Levaquin)FDA Link 01/2008
1	Ciprofloxacin (Cipro)FDA LinkGeneric 01/2008
1	EnzymesIBA 01/2008
1	Interleukin-6 (Interleukin 6)IBA 01/2008
1	Moxifloxacin (Avelox)FDA Link 01/2008

Therapy/Procedure

12	Artificial Respiration (Mechanical Ventilation) 01/2020 - 06/2002
4	Therapeutics 08/2018 - 07/2006
3	Catheters 04/2012 - 06/2006
2	Resuscitation 07/2009 - 07/2006
1	Blood Transfusion (Blood Transfusions) 10/2020
1	Palliative Care (Palliative Therapy) 10/2020
1	Radiotherapy 01/2020
1	Early Ambulation 01/2017
1	Length of Stay 01/2017
1	Positive-Pressure Respiration (Positive End-Expiratory Pressure) 12/2014
1	Noninvasive Ventilation 02/2012
1	Drug Therapy (Chemotherapy) 12/2010
1	Mechanical Ventilators (Ventilator) 02/2010
1	Tracheostomy 10/2009